NCT05019092

Systematic Screening for Deep Vein Thrombosis in Critically Ill Patients

Potential Harms and Benefits of Systematic Screening for Deep Vein Thrombosis in Critically Ill Patients

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Ettore Marini · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Background: venous thromboembolism (VTE) is a common complication in critically ill patients, admitted to the Intensive Care Units (ICUs). At the present time, there is no validated score to estimate risks and benefits of antithrombotic pharmacological prophylaxis in this subset of patients. Aim of the study: investigating potential harms and benefits of a protocol for systematic screening of DVT in critically ill patients, admitted to an ICU. Expected relevance: systematic screening for deep vein thrombosis (DVT) through ultrasound (US) lower limb veins examination could help defining the indication to antithrombotic pharmacological treatment, but no protocol of systematic screening has been validated so far. Furthermore, the screening could be associated with over-diagnosis and consequent over-treatment, as well as increased management burden for the caregivers and higher healthcare costs.

Conditions

• Deep Vein Thrombosis

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Ultrasound examination of lower limb veins	Ultrasound examination will be performed by trained physicians using a commercially available ultrasound system and 5.0-15.0 MHz linear probe. The examinations consists of a comprehensive B-mode ultrasound protocol, from thigh to ankle, employing compression and color-Doppler at selected sites, according to the Consensus Conference of the Society of Radiologists in Ultrasound.

Timeline

• Start date: 2021-01-01
• Primary completion: 2021-06-30
• Completion: 2021-12-31
• First posted: 2021-08-24
• Last updated: 2021-08-24

Locations

1 site across 1 country: Italy