NCT05018923

Tetracycline Versus Doxycycline for HP Rescue Therapy

Bismuth Quadruple Therapy With Tetracycline Versus Doxycycline as Rescue Therapy for Helicobacter Pylori Infection: a Randomized Controlled Trial

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 242 (estimated)
• Sponsor: Shanghai Zhongshan Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

This randomized controlled clinical trial will evaluate the efficacy and safety of proton pump inhibitor, bismuth, metronidazole, and either tetracycline or doxycycline for Helicobacter pylori rescue treatment. The completion of this trial will expand new therapy for the treatment of Helicobacter pylori.

Conditions

• Helicobacter Pylori Infection

Interventions

Type	Name	Description
DRUG	Rabeprazole	20mg bid
DRUG	Bismuth potassium citrate	0.6g bid
DRUG	Metronidazole	0.4g qid
DRUG	Doxycycline	0.1g bid
DRUG	Tetracycline	0.5g qid

Timeline

• Start date: 2021-08-24
• Primary completion: 2022-12-30
• Completion: 2022-12-30
• First posted: 2021-08-24
• Last updated: 2021-08-26

Locations

1 site across 1 country: China