NCT05018611

Digital Limited Interaction Efficacy Trial of LifeSkills Mobile to Reduce HIV Incidence in YTW

Digital, Limited Interaction Efficacy Trial of LifeSkills Mobile to Reduce HIV Incidence in Young Transgender Women

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 5,100 (estimated)
• Sponsor: University of California, Los Angeles · Academic / Other
• Sex: Male
• Age: 16 Years – 29 Years
• Healthy volunteers: Accepted

Summary

The LifeSkills Mobile app will be evaluated in a randomized controlled trial (RCT) among 5,000 young transgender women (YTW), ages 16-29 in the United States (U.S.). Study findings will demonstrate if the intervention will reduce HIV incidence.

Detailed description

LifeSkills Mobile is an mHealth intervention to promote biobehavioral HIV prevention strategies based on empowerment theory and was developed using a community-based participatory research approach. An RCT assesses the efficacy of the LifeSkills Mobile intervention in comparison to a standard of care (SOC) condition among 5,000 YTW recruited online. At baseline and every 6 months through 12-48 months (depending on when the participant enrolled), enrolled participants will complete an online survey sent via a link to their mobile phone and will be mailed an OraQuick In-Home HIV Test kit. We will also estimate the total and incremental costs of the LifeSkills Mobile intervention relative to SOC, from healthcare sector and societal perspectives.

Conditions

• HIV Prevention

Interventions

Type	Name	Description
BEHAVIORAL	LifeSkills Mobile	A mobile app designed to facilitate the broad reach and impact of the LifeSkills intervention to reduce sexual risk behavior which drives HIV infection. The LifeSkills intervention addresses the specific structural, developmental, and interpersonal challenges to HIV prevention among YTW ages 16-29, with prior evidence of the efficacy to reduce sexual risk.

Timeline

• Start date: 2022-01-22
• Primary completion: 2027-02-28
• Completion: 2027-02-28
• First posted: 2021-08-24
• Last updated: 2026-03-31

Locations

1 site across 1 country: United States