NCT05016518

Comparison of Quality of Recovery (QoR)-15 Scores Between Propofol and Remimazolam Anesthesia

Comparison of Quality of Recovery (QoR)-15 Scores According to the Use of Anesthetics During Total Intravenous Anesthesia in Female Patients Undergoing Thyroid Surgery

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 140 (actual)
• Sponsor: Gangnam Severance Hospital · Academic / Other
• Sex: Female
• Age: 20 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Remimazolam is a ultra-short-acting benzodiazepine that is rapidly metabolized in the body by tissue esterase and not accumulates in the body for long periods of infusion. In addition, similar to other benzodiazepines, it is possible to reverse the sedation and anesthetic effects through flumazenil. It has no injection pain and infusion syndrome compared with propofol. There is no study to investigate overall postoperative functional recovery via QoR-15 in patients receiving TIVA using remimazolam. The purpose of this study is to determine whether there is any difference in the quality of postoperative recovery between propofol-based and remimazolam-based total intravenous anesthesia in female patients undergoing thyroidectomy. The QoR-15 questionnaire score, pain, nausea/vomiting, and the frequency of complications are evaluated and compared between the two groups.

Conditions

• Patients Undergoing Thyroid Surgery for Neoplasm

Interventions

Type	Name	Description
DRUG	Arm I (Propofol group)	Propfol group will be started and maintained total intravenous anesthesia with propofol and remifentanil .
DRUG	Arm II (Remimazolam group)	Remimazolam group will be started and maintained total intravenous anesthesia with remimazolam and remifentanil.

Timeline

• Start date: 2021-09-16
• Primary completion: 2022-05-18
• Completion: 2022-05-20
• First posted: 2021-08-23
• Last updated: 2022-06-01

Locations

1 site across 1 country: South Korea