NCT05013957

Neuroendocrine Neoplasms Methylation Based Classifier - The NEMESIs-study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 32 (actual)
• Sponsor: University Hospital, Basel, Switzerland · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

Neuroendocrine neoplasms (NEN) are rare tumors that mainly occur in the gastrointestinal tract and the lungs. The currently available diagnostic and prognostic markers do not adequately represent the diversity of these tumors. Methylation analyzes of the tumor DNA represent a new, promising approach. The aim of this project is therefore to improve the diagnostic and prognostic evaluation of neuroendocrine neoplasms by means of methylation analysis of the tumor DNA. On the one hand, existing tumor samples from the biobank of Basel University Hospital are evaluated, on the other hand, patients who are undergoing an operation will be prospectively inquired

Conditions

• Neuroendocrine Tumors

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Methylation analysis	Methylation analysis

Timeline

• Start date: 2022-01-01
• Primary completion: 2024-12-30
• Completion: 2024-12-30
• First posted: 2021-08-20
• Last updated: 2025-01-29

Locations

1 site across 1 country: Switzerland