Trials / Withdrawn
WithdrawnNCT05013320
Combined Dexmedetomidine and Glycopyrrolate Therapy
Combined Dexmedetomidine and Glycopyrrolate Therapy for Prevention of Catheter Related Bladder Discomfort After Transurethral Bladder Surgery
- Status
- Withdrawn
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 0 (actual)
- Sponsor
- Kangbuk Samsung Hospital · Academic / Other
- Sex
- All
- Age
- 19 Years
- Healthy volunteers
- Not accepted
Summary
Catheter-related bladder discomfort after transurethral resection of bladder tumor is frequent because of indwelling urinary catheter for irrigation. The mechanism of the catheter-related bladder discomfort is similar to that of overactive bladder, in which muscarinic acetylcholine receptors are stimulated. The catheter-related bladder discomfort is a well known predisposing factor for emergence delirium after general anesthesia. In this study, we aimed to compare the incidence of catheter-related bladder discomfort between dexmedetomidine only therapy and combind dexmedetomidine and glycopyrrolate therapy.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Glycopyrrolate + dexmedetomidine | Intravenous glycopyrrolate before anesthetic induction. Dexmedetomidine administration during the surgery. |
| DRUG | Dexmedetomidine | Dexmedetomidine administration during the surgery. |
Timeline
- Start date
- 2021-09-01
- Primary completion
- 2022-12-31
- Completion
- 2022-12-31
- First posted
- 2021-08-19
- Last updated
- 2021-08-19
Source: ClinicalTrials.gov record NCT05013320. Inclusion in this directory is not an endorsement.