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Trials / Completed

CompletedNCT05012436

A Study to Evaluate the Pharmacokinetics and Safety of YHD1119 in Subjects With Renal Impairment and Healthy Subjects

A Study to Evaluate the Pharmacokinetics and Safety Following a Single Oral Dose of YHD1119 in Subjects With Renal Impairment and Healthy Subjects

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
16 (actual)
Sponsor
Yuhan Corporation · Industry
Sex
All
Age
19 Years – 75 Years
Healthy volunteers
Accepted

Summary

The purpose of this trial is to compare the pharmacokinetic characteristics and safety of YHD1119(Pregabalin SR 75mg) and YHD1119(Pregabalin SR 150mg) in subjects with renal impairment and healthy subjects. YHD1119 is sustained-release (SR) formulation which is made by Yuhan Corporation. Primary endpoints are Cmax and AUClast and secondary endpoints are AUCinf,Tmax, t1/2, CL/F and V/F.

Conditions

Interventions

TypeNameDescription
DRUGYHD1119 75mgA single oral dose

Timeline

Start date
2021-07-24
Primary completion
2022-05-10
Completion
2022-05-10
First posted
2021-08-19
Last updated
2022-06-30

Locations

2 sites across 1 country: South Korea

Source: ClinicalTrials.gov record NCT05012436. Inclusion in this directory is not an endorsement.

A Study to Evaluate the Pharmacokinetics and Safety of YHD1119 in Subjects With Renal Impairment and Healthy Subjects (NCT05012436) · Clinical Trials Directory