NCT05010941

Hypotension Prediction Index in Living Donor Liver Transplantation

Performance of the Hypotension Prediction Index in Living Donor Liver Transplantation

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 20 (actual)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 20 Years
• Healthy volunteers: Not accepted

Summary

The Hypotension Prediction Index via the Edwards Hemosphere advanced monitoring system is monitored in living donor liver transplantation recipients. The Hypotension Prediction Index is analyzed to verify the performance in predicting hypotensive events.

Detailed description

Hypotensive events during surgery and anesthesia occur frequently and are associated with complications such as myocardial infarction, acute kidney injury, and increase in mortality. Therefore predicting and preventing hypotension can lead to better outcomes. The Hypotension Prediction Index is monitored with the Edwards Hemosphere advanced monitoring system in living donor liver transplantation recipients via the radial artery. The monitor is blinded so that the anesthesiologist cannot see the index, and the anesthesiologist manages the blood pressure according to the institution's anesthetic protocol for liver transplantation. After the surgery is done, the Hypotension Prediction Index is analyzed to see how well the index predicted actual hypotension that occured during the liver transplantation surgery. Receiver operating characteristic curves are drawn to show the performance of the Hypotension Prediction Index in liver transplantation.

Conditions

• Living Donor Liver Transplantation
• Hypotension

Interventions

Type	Name	Description
DEVICE	Hypotension Prediction Index	Hypotension Prediction Index monitored via radial arterial line

Timeline

• Start date: 2021-08-13
• Primary completion: 2022-03-12
• Completion: 2022-03-12
• First posted: 2021-08-18
• Last updated: 2022-05-05

Locations

1 site across 1 country: South Korea