NCT05007756

A Study Exploring the Use of Challenge Agents in Healthy Volunteers or Participants With a Disease of Interest

A Phase 0 Platform Study Exploring the Use of Challenge Agents in Healthy Volunteers or Participants With a Disease of Interest

• Status: Completed
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 24 (actual)
• Sponsor: Janssen Research & Development, LLC · Industry
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to characterize the biological response in vivo to challenge agents (vaccines, antigen, drug, or mechanical challenges); to assess the safety and tolerability of the challenge agent and to characterize the immune response in skin elicited in vivo in healthy volunteers using an ultraviolet B (UVB) challenge.

Conditions

• Healthy

Interventions

Type	Name	Description
RADIATION	UVB Challenge	UVB challenge will be administered dermally through Lumera Phototherapy System.

Timeline

• Start date: 2021-07-14
• Primary completion: 2021-11-04
• Completion: 2021-11-04
• First posted: 2021-08-16
• Last updated: 2021-12-10

Locations

1 site across 1 country: Belgium