NCT05007405

Spectrum of Bacterial Infections in Rheumatology

Spectrum of Bacterial Infections in Rheumatology and the Role of Urinary Tract Infection

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 81 (actual)
• Sponsor: Hôpital NOVO · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Retrospective study of patients with a proved non-tuberculous osteoarticular infection (OAI) diagnosed in a rheumatology department during the years 2010-2020. The objectives are : * To describe sites, type of micro-organism, clinical data, origin of infection, therapeutic modalities et outcome * To compare OAI of urinary origin with those with another origin

Detailed description

This retrospective study will be conducted on medical files. Patients will be mainly selected on : * A proved osteoarticular infection (OAI) diagnosed in the department of rheumatology of the René Dubos hospital from 1° January 2010 to 31 December 2020. * Adult patients 18 year's old or older * Infection proved by positive culture in the osteoarticular site and/or blood (with typical clinical and imaging features) The followed OAI are not included : * Infection on prosthetic joint, materiel ; post-operative OAI ; osteomyelitis * Brucellosis ; Lyme disease Patients are selected from the codification of the hospitalization ; medical files are reviewed by the investigators. OAI of urinary origin is defined either by the same micro-organism in urine and osteo-articular sample (or blood) or a bacteria in the osteo-articular sample in conjunction with : urologic pathology, recurrent urinary tract infection, urologic surgery, antibiotic therapy. * Characteristics of three populations will be compared : * \- OAI of urinary origin * \- OAI of another origin (skin, etc) * \- OAI without known origin Characteristics include : gender, age, risk factors, site of osteo-articular infection, type of micro-organism, type of positive sample(s), blood cultures, urinary cultures, duration of symptoms, site of primary infection and/or type of contamination, biological results, echocardiography, imaging results, type of treatment (medical, surgical), outcome, duration of hospitalization, intensive unit care stay, death at hospital.

Conditions

• Articular Disease

Interventions

Type	Name	Description
OTHER	Groups/Cohortes	Retrospective study on medical file of patients with osteoarticular infections diagnose (date of the positive bacteriological sample) between January 1, 2010 and December 31, 2020

Timeline

• Start date: 2021-02-12
• Primary completion: 2021-12-31
• Completion: 2021-12-31
• First posted: 2021-08-16
• Last updated: 2024-09-19

Locations

1 site across 1 country: France