NCT05006378

Effect of Chamomile Intake on Blood Coagulation Tests in Healthy Volunteers

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 12 (actual)
• Sponsor: Stony Brook University · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

Chamomile may possess anticoagulant effects based on the presence of coumarin-like compounds within the flower. This randomized, placebo-controlled complete crossover study will investigate the impact of chamomile ingestion on coagulation.

Detailed description

Subjects will be enrolled into three groups in a crossover fashion upon obtaining written informed consent. Baseline laboratory screening assays of anticoagulation will be obtained. The three intervention groups include (1) chamomile tea intake, (2) chamomile extract intake and (3) placebo capsules. Subjects will consume the chamomile or placebo preparations for one week and partake in a one-week washout period between interventions. Screening assays of coagulation will be obtained immediately before and after each intervention week.

Conditions

• Coagulation Disorder

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Chamomile Tea	Chamomile tea bags consumed by subjects as described in study arms section.
DIETARY_SUPPLEMENT	Chamomile Extract Capsule	Chamomile extract capsules consumed by subjects as described in "Experimental: Chamomile Extract Capsule" study arms section.
DIETARY_SUPPLEMENT	Placebo Capsule	Placebo capsules consumed by subjects as described in "Placebo Comparator" study arms section.

Timeline

• Start date: 2021-08-31
• Primary completion: 2022-01-19
• Completion: 2022-01-19
• First posted: 2021-08-16
• Last updated: 2022-02-10

Locations

1 site across 1 country: United States