Trials / Unknown
UnknownNCT05002764
Thalamic Nuclei Volumes in Multiple Sclerosis
Differential Vulnerability of Individual Thalamic Nuclei: Toward New Biomarkers in Multiple Sclerosis
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 2,000 (estimated)
- Sponsor
- University Hospital, Bordeaux · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- —
Summary
The thalamus is composed of several nuclei interlocked in a complex anatomy. In multiple sclerosis (MS), the thalamus can be altered due to disconnection by white matter lesions and due to direct damages that could be partly mediated by CSF. Due to such pathophysiology and complex anatomy, some nuclei could be more vulnerable to multiple sclerosis than others. We will test this hypothesis by using a new algorithm to automatically segment several nuclei that we will be applied to the French national MS database
Conditions
Timeline
- Start date
- 2021-07-01
- Primary completion
- 2023-07-01
- Completion
- 2023-07-01
- First posted
- 2021-08-12
- Last updated
- 2021-08-12
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT05002764. Inclusion in this directory is not an endorsement.