Clinical Trials Directory

Trials / Completed

CompletedNCT05002621

Changes in Gene Transcription and Immunophenotypes Following Mepolizumab Treatment for Asthma

Exploratory Investigation of Changes in Gene Transcription and Immunophenotypes Following Mepolizumab Treatment for Asthma

Status
Completed
Phase
Study type
Observational
Enrollment
20 (actual)
Sponsor
Mayo Clinic · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

The purpose of this study is to identify differentially expressed gene transcripts after initiation of mepolizumab in individuals with severe eosinophilic asthma (SEA).

Conditions

Interventions

TypeNameDescription
OTHERObservationalEnrolled patients had a prescription for mepolizumab provided during the course of routine clinical care, and enrollment occurred prior to the initiation of mepolizumab.

Timeline

Start date
2021-02-16
Primary completion
2023-02-13
Completion
2025-12-11
First posted
2021-08-12
Last updated
2026-03-18
Results posted
2026-03-18

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT05002621. Inclusion in this directory is not an endorsement.