Trials / Completed
CompletedNCT04997876
Diagnostic Reliability of OCT Biomarkers for iERM
Diagnostic Reliability of OCT Biomarkers for Idiopathic Epiretinal Membranes
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 136 (actual)
- Sponsor
- Vienna Institute for Research in Ocular Surgery · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Several optical coherence tomography (OCT) biomarkers with potential to influence postsurgical outcomes after vitrectomy with membrane peeling for idiopathic epiretinal membranes (iERM) have been described in single predictor analyses in the past. Aim of the study is to assess the reliability of diagnosis of OCT biomarkers and to calculate their impact on postsurgical visual acuity in a multiple regression analysis.
Detailed description
Several optical coherence tomography (OCT) biomarkers with potential to influence postsurgical outcomes after vitrectomy with membrane peeling for idiopathic epiretinal membranes (iERM) have been described in single predictor analyses in the past. A recent multifactorial analysis outlined macular thickness and DRIL to be significant predictors for postsurgical visual acuity (Karasavviodou et al.). Nevertheless, reliability of diagnosing OCT biomarkes among patients with iERM was not yet assessed, to our knowledge. Aim of the study is to assess the reliability of diagnosis of OCT biomarkers and to calculate their impact on postsurgical visual acuity in a multiple regression analysis.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Biomarker analysis | Biomarkers from presurgical OCTs are assessed |
Timeline
- Start date
- 2021-01-11
- Primary completion
- 2021-08-05
- Completion
- 2021-08-21
- First posted
- 2021-08-10
- Last updated
- 2021-08-24
Locations
1 site across 1 country: Austria
Source: ClinicalTrials.gov record NCT04997876. Inclusion in this directory is not an endorsement.