NCT04997642

Parkinson's Disease and Movement Disorders Clinical Database

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 250 (estimated)
• Sponsor: University of Pennsylvania · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The research database contains demographic and family history information, longitudinal information on the clinical symptoms, neuropsychological profile and treatments, stored biological samples, and brain images of patients with Parkinson's disease and related disorders receiving care at the Parkinson's disease and Movement Disorders Center and the Hospital of the University of Pennsylvania.

Detailed description

The research database contains demographic and family history information, longitudinal information on the clinical symptoms, neuropsychological profile and treatments, stored biological samples, and brain images of patients with Parkinson's disease and related disorders receiving care at the Parkinson's disease and Movement Disorders Center (PDMDC) and the Hospital of the University of Pennsylvania. The purpose of the research database is to have a comprehensive source of data that can be used for educational, research and patient care projects at the PDMDC. These data may be used for any study examining the relationship between treatment and clinical symptoms of patients with PD and related disorders. The main uses of the data are to: * Determine the long term effects of Parkinson's disease and related conditions, including predictors of its motor and non-motor symptoms * Identify genetic and other neurobiological factors related to the risk of developing Parkinson's disease and related disorders and their course * Improve our understanding of how best to identify, diagnose, and manage motor and non-motor symptoms of Parkinson's disease and related conditions Evaluate biological markers of disease or response to therapy * Identify patients who may be candidates for participation in trials of new medications. * Identify patients who may be interested in participating in educational or developmental activities Participants are seen annually for the first 4 years, biennially thereafter. The participants continue in the study until study end, withdrawal, or death on study.

Conditions

• Parkinson Disease
• Parkinson Disease Dementia
• Lewy Body Parkinson Disease
• Lewy Body Dementia With Behavioral Disturbance

Interventions

Type	Name	Description
BEHAVIORAL	neuropsychiatric and cognitive testing questionnaires	Demographic data such as race, sex, age Family History Risk Factor Questionnaire Hoehn and Yahr Stage UPDRS Parkinson's symptom checklist Medication list Neuropsychological Test Battery Behavioral Exams * Geriatric Depression Scale Quality of Life Questionnaire * PDQ-39, SF-12

Timeline

• Start date: 2019-09-30
• Primary completion: 2029-09-15
• Completion: 2029-09-15
• First posted: 2021-08-09
• Last updated: 2025-10-07

Locations

1 site across 1 country: United States