NCT04996147

Acute and Long-term Impact of Cancer Treatment on Head and Neck Cancer Patients: FIT4TREATMENT

Acute and Long-term Impact of Cancer Treatment on Quality-of-life, Physical and Cognitive Function of Head and Neck Cancer Patients

• Status: Terminated
• Phase: —
• Study type: Observational
• Enrollment: 21 (actual)
• Sponsor: Associacao de Investigacao de Cuidados de Suporte em Oncologia · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: —

Summary

Head and Neck Squamous Cell Carcinoma (HNSCC) is the 6th most common cancer. Most cases are diagnosed in locally advanced stages, with treatment involving multimodal approach with combinations of radiotherapy, surgery and chemotherapy. The aggressive nature of HNSCCs and treatment modalities are associated with important acute and late toxicities that often promote temporary or definitive treatment interruption and may compromised the capability to tolerate subsequent treatments. Thus, the aim of this study is to analyze the acute and long-term impact of cancer treatment on quality of life, physical and cognitive function of HNSCC patients diagnosed with a locally advanced disease.

Detailed description

Potential cases will be identified at the multidisciplinary head and neck group meeting. If the case meets eligibility an informed consent will be presented to the patient. Interested participants will be scheduled for baseline assessment before the beginning of treatment (M0). At the end of CRT patients will be submitted to a second assessment (M1). Follow-up assessments will occur 16th to 18th weeks after the treatment is completed (M2). Patients proposed to surgery or induction chemotherapy will also be submitted to an additional assessment before the beginning of CRT (Mc / Mic).

Conditions

• Head and Neck Neoplasms

Timeline

• Start date: 2019-06-01
• Primary completion: 2020-03-03
• Completion: 2020-03-03
• First posted: 2021-08-09
• Last updated: 2021-08-09

Locations

1 site across 1 country: Portugal