NCT04994379

Investigating the Effects of Intensity of Transcranial Direct Current Stimulation on Subjective Appetite

Investigating the Effect of the Intensity of Primary Motor Cortex Cathodal TDCS on Appetite; a Double-blind Sham-controlled Study

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 64 (actual)
• Sponsor: University of Messina · Academic / Other
• Sex: All
• Age: 18 Years – 35 Years
• Healthy volunteers: Accepted

Summary

This is a randomized double-blind sham controlled systematic investigation to understand the importance of the brain region that controls the tongue and the submental muscle region on perceived appetite. The results of this study can have clinical implications for a phenomenon called hyperphagia.

Detailed description

After explaning all the procedure and the scientific aims of the project to participants and completing the informed consent form, each participant will be randomly asked to take part in the experiment while fasting for at least 6 hours or completely sated, to enable an investigation of the role of the basic level of hunger on the effects of brain stimulation on subjective appetite. Different intensities of stimulation (1 mA, 1.5 mA, and sham) will be used in three separate groups, to which participants will be randomly assigned, in a double-blind manner.

Conditions

• Healthy

Interventions

Type	Name	Description
DEVICE	1 mA tDCS	One session with stimulation intensity of 1 mA.
DEVICE	1.5 mA tDCS	One session with stimulation intensity of 1.5 mA.
DEVICE	Sham tDCS	One session of sham stimulation.

Timeline

• Start date: 2021-08-01
• Primary completion: 2021-09-01
• Completion: 2022-02-01
• First posted: 2021-08-06
• Last updated: 2024-12-16

Locations

1 site across 1 country: Italy