Trials / Unknown
UnknownNCT04993378
Prospectively Predict the Efficacy of Treatment of Gastrointestinal Tumors Based on Peripheral Multi-omics Liquid Biopsy
A Clinical Study Initiated by Investigator:Prospectively Predict the Efficacy of Precise Treatment of Gastrointestinal Tumors Based on Peripheral Blood Multi-omics Liquid Biopsy
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 40 (estimated)
- Sponsor
- Shen Lin · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
To vertify the function of EV-score on predicting \& monitoring immunotherapeutic outcomes of GC
Detailed description
Our previous work identified four plasma EV-derived proteins and combined them to generate a signature score that robustly predicting immunotherapeutic outcomes at baseline and dynamically monitoring disease progressions along with the whole treatment. Hence in this stuty, we plan to recruit a prospective cohort to support our conclusions, and provide possible method to realize predicting and monitoring immunotherapeutic outcomes of GC.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | EV-array | Collect peripheral blood sample of 40 gastric cancer patients pre-treatment. Blood samples will be transferred to central lab to detect EV-score by EV-array. Tumor response evaluation will be performed after two cycles of chemotherapy by CT/MRI based on RECIST. Clinical data, including tumor stage, metastastic organ, regimen, objective response, progression free survival, overall survival, etc, will be collected according to study protocol. |
Timeline
- Start date
- 2018-11-01
- Primary completion
- 2021-04-30
- Completion
- 2021-07-30
- First posted
- 2021-08-06
- Last updated
- 2021-08-06
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT04993378. Inclusion in this directory is not an endorsement.