NCT04991064

Retention of Maxillary Complete Dentures Modified With Titanium Dioxide Nanoparticles: A Randomized Crossover Clinical Trial.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 10 (actual)
• Sponsor: Cairo University · Academic / Other
• Sex: All
• Age: 45 Years – 55 Years
• Healthy volunteers: Accepted

Summary

This study investigates the effect of the addition of titanium dioxide nanoparticles to denture base materials on their retention compared to that of the unmodified denture base materials.

Detailed description

All patients will be randomly allocated to two equal groups either with the protocol I or II (5 in each group) with an allocation ratio of 1:1 through a computer-generated sequence by a spreadsheet (Excel, Microsoft Office 2010; Microsoft Corp). The group with the protocol I will use the modified dentures with titanium dioxide nanoparticles (TiO2NP) during the first month, followed by no use of the first denture and the use of their old relined dentures instead for 1 month (washout), and then the use of the unmodified dentures for 1 month; the group with the protocol II will use the unmodified dentures during the first month, followed by no use of the first denture and the use of their old relined dentures instead for 1 month (washout), and then the use of the modified dentures TiO2NP for 1 month. Assessment of retention will be done immediately and 1 month after denture insertion.

Conditions

• Denture Retention
• Complete Dentures

Interventions

Type	Name	Description
OTHER	Complete denture base modified by Titanium dioxide nanoparticles.	Titanium dioxide nanoparticles will be mixed with resin powder of the denture base before mixing the powder and liquid of the heat cure denture base material.

Timeline

• Start date: 2017-02-12
• Primary completion: 2017-06-03
• Completion: 2017-06-15
• First posted: 2021-08-05
• Last updated: 2021-09-20

Locations

1 site across 1 country: Egypt