NCT04990817

Effects of Replacing Energy From Solid Fats and Added Sugars (SoFAS) With Avocado

A Randomized, Controlled-feeding, Double-blind, Crossover Study to Examine the Metabolic Effects of Replacing Energy From Solid Fats and Added Sugars (SoFAS) With Avocado in Men and Women With Elevated Triglycerides

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 42 (actual)
• Sponsor: Midwest Center for Metabolic and Cardiovascular Research · Academic / Other
• Sex: All
• Age: 21 Years – 74 Years
• Healthy volunteers: Accepted

Summary

The objective of this study is to assess the effects of replacing energy from SoFAS with energy from avocado on non-high-density lipoprotein cholesterol (non-HDL-C) and other aspects of the cardiometabolic health profile including fasting lipoprotein lipid and particle concentrations, insulin sensitivity and blood pressure in men and women with elevated triglycerides (TG).

Conditions

• Elevated Triglycerides
• Hypertriglyceridemia

Interventions

Type	Name	Description
OTHER	Average American Diet With SoFAS Replaced With Avocado	Replacing energy from solid fats and added sugars (SoFAS) with Avocado as part of an average American diet
OTHER	Average American Diet	Average American diet based on macronutrient analyses from the most recent Nutrition and Health Examination Survey.

Timeline

• Start date: 2021-06-18
• Primary completion: 2024-04-17
• Completion: 2024-04-17
• First posted: 2021-08-05
• Last updated: 2024-05-21

Locations

2 sites across 1 country: United States