NCT04989257

24-month Ticagrelor-based Dual-antiplatelet Therapy Versus Clopidogrel-based Dual-antiplatelet theRapy aftEr 12 Months of DrUg-eluting Stent Implantation in High isChEmic Risk Patients: P-REDUCE Trial

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 3,488 (estimated)
• Sponsor: Yonsei University · Academic / Other
• Sex: All
• Age: 50 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this prospective randomized clinical trial is to compare the clinical outcomes between aspirin with ticagrelor versus aspirin with clopidogrel in high ischemic risk patients beyond 12 months after percutaneous coronary intervention with drug-eluting stent implantation

Conditions

• High Ischemic Risk

Interventions

Type	Name	Description
DRUG	Ticagrelor-based dual-antiplatelet therapy	Aspirin with ticagrelor
DRUG	Clopidogrel-based dual-antiplatelet therapy	Aspirin with clopidogrel

Timeline

• Start date: 2021-08-01
• Primary completion: 2026-06-01
• Completion: 2026-06-01
• First posted: 2021-08-04
• Last updated: 2021-08-04

Locations

1 site across 1 country: South Korea