NCT04989192

Dose Efficiency of Modern CT Scanners in Oncologic Scans

On Dose Efficiency of Modern CT-Scanners in the Staging of Malignancies - a Prospective Randomized Study

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 2,400 (estimated)
• Sponsor: University Hospital Augsburg · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

CT-Staging is crucial for therapy planning of patients with malignancies. Dose efficiency and image quality are important parameters for these examinations. Up to now, scientific evidence of dose efficiency of modern CT scanners is mostly derived from retrospective analyses. This prospective study systematically analyzes dose efficiency and image quality of three modern CT scanners by randomization of patients who are scheduled for a CT scan to examine the status of malignancies. After giving informed consent and randomization (1:1:1), the CT scan will be performed at one of the modern CT scanners available at our department. This will allow a systematic allocation to the different scanners.

Conditions

• Neoplasms
• Neoplasm Metastasis
• Metastatic Cancer

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Scan at CT scanner 1	Patients will undergo imaging on a modern CT scanner with spectral imaging capabilities. A dose neutral spectral acquisition mode will routinely be used. Contrast material protocol and scan ranges are similar among all three arms.
DIAGNOSTIC_TEST	Scan at CT scanner 2	Patients will undergo imaging on a modern 128 slice CT-scanner without spectral imaging capabilities. A standard acquisition protocol will be used. Contrast material protocol and scan ranges are similar among all three arms.
DIAGNOSTIC_TEST	Scan at CT scanner 3	Patients will undergo imaging on a modern 20 slice CT-scanner without spectral imaging capabilities. A standard acquisition protocol will be used. Contrast material protocol and scan ranges are similar among all three arms.

Timeline

• Start date: 2021-08-17
• Primary completion: 2022-08-17
• Completion: 2023-08-17
• First posted: 2021-08-04
• Last updated: 2021-08-18

Locations

1 site across 1 country: Germany