NCT04989166

Effect of Nano-curcumin Supplementation in Acute Pancreatitis

Effect of Nano-curcumin Supplementation on Hospital Length of Stay, Clinical Outcomes,and Inflammation Level in Mild and Moderate Acute Pancreatitis.

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 42 (actual)
• Sponsor: National Nutrition and Food Technology Institute · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

This study aims to investigate the effect of nano-curcumin supplementation on hospital length of stay, clinical outcomes, and inflammation level in mild and moderate acute pancreatitis. 42 eligible patients with mild and moderate acute pancreatitis will randomly assign to consume two soft gels each containing 40 mg of nano-curcumin or placebo (control group) every morning and evening for two weeks. Both groups will also receive the standard medical treatment of acute pancreatitis according to relevant guidelines. Patient's blood samples and clinical outcomes will assess on days 0, 1, 2, 3, 4, and 14 of admission. The two groups will also be compared in terms of adverse events and hospital length of stay. Moreover, the patient's hospital readmission due to pancreatitis will be recorded within 90 days of hospitalization.

Detailed description

The dietary intake of patients will be examined by two non-consecutive 24-hour food recalls at baseline and end of the study. The patient's weight (kg) and Body Mass Index (BMI) will also be measured.

Conditions

• Acute Pancreatitis

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Nano-curcumin	Nano-curcumin soft gels
DRUG	Placebo	Placebo

Timeline

• Start date: 2021-10-19
• Primary completion: 2022-10-15
• Completion: 2023-01-15
• First posted: 2021-08-04
• Last updated: 2022-12-07

Locations

1 site across 1 country: Iran