Clinical Trials Directory

Trials / Completed

CompletedNCT04988958

Radical Versus Conservative Surgical Treatment of Liver Hydatid Cysts

Radical Versus Conservative Surgical Treatment of Liver Hydatid Cysts: A Propensity Score Matching Analysis

Status
Completed
Phase
Study type
Observational
Enrollment
914 (actual)
Sponsor
Université de Sousse · Academic / Other
Sex
All
Age
14 Years
Healthy volunteers
Not accepted

Summary

The management of liver hydatid cysts (LHC) is controversial. Surgery remains the basic treatment, and can be divided into radical and conservative approaches. The purpose of this study was to compare the outcome of radical and conservative surgery (CS) in the treatment of LHC and to evaluate the efficiency and safety of radical surgery (RS).

Detailed description

The management of liver hydatid cysts (LHC) is controversial. Surgery remains the basic treatment, and can be divided into radical and conservative approaches. The purpose of this study was to compare the outcome of radical and conservative surgery (CS) in the treatment of LHC and to evaluate the efficiency and safety of radical surgery (RS). Data from all patients with LHC treated in Sahloul Hospital, between January 2000 and December 2019, were retrieved from a retrospective database. To minimize selection bias, propensity score matching (PSM) was performed, based on variables representing patient characteristics and operative risk factors. RS especially total pericystectomy had fewer postoperative complications and lower recurrence rate compared to CS. RS may be the preferred procedure for LHC if the expertise is available.

Conditions

Interventions

TypeNameDescription
PROCEDUREhydatid cyst resectionradical resection of hydatic cyst

Timeline

Start date
2000-01-01
Primary completion
2019-12-31
Completion
2019-12-31
First posted
2021-08-04
Last updated
2021-08-04

Source: ClinicalTrials.gov record NCT04988958. Inclusion in this directory is not an endorsement.