Trials / Completed
CompletedNCT04983160
Crossover Clinical Trial, Randomized, Double Blind, Placebo Controlled Trial
Crossover Clinical Trial, Randomized, Double Blind, Placebo Controlled Trial. Modulation of Cellular Mediators and Repair Endothelial Damage in Patients With Chronic Renal Disease Through Inhibition of Xanthine Oxidase
- Status
- Completed
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 22 (actual)
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba · Academic / Other
- Sex
- All
- Age
- 18 Years – 70 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to determine the effect of inhibiting xanthine oxidase with allopurinol in patients with chronic kidney disease in asymptomatic hyperuricemia endothelial injury and vascular repair mechanisms.
Detailed description
The purpose of this study is to determine the effect of inhibiting xanthine oxidase with allopurinol in patients with chronic kidney disease in asymptomatic hyperuricemia endothelial injury and vascular repair mechanisms, evaluating the plasma concentration of angiogenic factors, microparticles of endothelial cells and the cell number circulating endothelial progenitor.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Allopurinol | Allopurinol |
| DRUG | Placebo | Placebo |
Timeline
- Start date
- 2014-02-26
- Primary completion
- 2016-04-29
- Completion
- 2016-04-29
- First posted
- 2021-07-30
- Last updated
- 2021-07-30
Locations
1 site across 1 country: Spain
Source: ClinicalTrials.gov record NCT04983160. Inclusion in this directory is not an endorsement.