NCT04980599

Effect of a Probiotic Strain Lactobacillus Paracasei K56 on Metabolic Symptom - a Pilot Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 118 (actual)
• Sponsor: Fudan University · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Accepted

Summary

Recent data suggest that gut microbiota can function as an environmental factor that modulates the amount of body fat and obese individuals have an altered gut microbiota.The results of previous animal studies have suggest that a probiotic strain Lactobacillus paracasei K56 have reduced high-fat diet induced obesity. In this before-after pilot study, the participants were randomly assigned to 8 groups to compare the fat-reducing effect of the Lactobacillus paracasei K56 by continuously supplementing different product prototypes , and screen the best probiotic K56 prototype with the effect of fat reduction.

Conditions

• Obesity
• Adiposity

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	probiotic drink with Lactobacillus paracasei K56	Probiotic drink (K56 10\^11CFU) 350ml/d for 60days
DIETARY_SUPPLEMENT	maltodextrin	maltodextrin ,for 60days
DIETARY_SUPPLEMENT	Probiotic powder E3	Probiotic powder 3.0g/d (K56 10\^10cfu) 60days;
DIETARY_SUPPLEMENT	Probiotic powder E5	probiotic powder 8g/day for 60days
DIETARY_SUPPLEMENT	probiotic capsule E7	probiotic k56 capsule, 2capsules/d (10\^7cfu) for 60days
DIETARY_SUPPLEMENT	probiotic capsule E9	probiotic k56 capsule, 2capsules/d (10\^9cfu) for 60days
DIETARY_SUPPLEMENT	probiotic capsule E10	probiotic k56 capsule, 2capsules/d (10\^10cfu) for 60days
DIETARY_SUPPLEMENT	probiotic capsule E11	probiotic k56 capsule, 4capsules/d (10\^11cfu) for 60days

Timeline

• Start date: 2021-01-10
• Primary completion: 2021-08-30
• Completion: 2021-12-31
• First posted: 2021-07-28
• Last updated: 2023-01-10

Locations

1 site across 1 country: China