Clinical Trials Directory

Trials / Unknown

UnknownNCT04979585

Camrelizumab Plus Amlotinib and Chemotherapy in the First-line Treatment of Melanoma

Camrelizumab Combined With Anlotinib and Nab-paclitaxel in Patients With Untreated Advanced Mucosal Melanoma:a Single-arm, Multicenter, Open-label Study

Status
Unknown
Phase
Phase 2
Study type
Interventional
Enrollment
66 (estimated)
Sponsor
Di Wu · Academic / Other
Sex
All
Age
18 Years – 75 Years
Healthy volunteers
Not accepted

Summary

To evaluate the objective response rate of camrelizumab combined with anlotinib and nab-paclitaxel in patients with untreated advanced mucosal melanoma.

Detailed description

The current traditional cytotoxic single agent or combination chemotherapy cannot clearly improve the overall survival rate of patients with advanced melanoma.From the current point of view, combination therapy will be one of the inevitable trends in the future development of tumor immunotherapy. So carry out this research To evaluate the objective response rate of camrelizumab combined with anlotinib hydrochloride and albumin paclitaxel in the first-line treatment of patients with advanced mucosal melanoma.

Conditions

Interventions

TypeNameDescription
DRUGCamrelizumab200mg ,IV,d1,Q3W.
DRUGAnlotinib8mg,oral, d1-14,Q3W.
DRUGnab-Paclitaxel260mg/m2,IV,d1,Q3W.

Timeline

Start date
2021-07-15
Primary completion
2023-04-14
Completion
2023-08-14
First posted
2021-07-28
Last updated
2021-08-03

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT04979585. Inclusion in this directory is not an endorsement.