NCT04979455

Risk Factors for Exertional Heat Illness

Prospective Investigation of Risk Factors for Exertional Heat Illness

• Status: Active Not Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 783 (estimated)
• Sponsor: Liverpool John Moores University · Academic / Other
• Sex: All
• Age: 17 Years – 35 Years
• Healthy volunteers: Accepted

Summary

The arduous nature of military training and operations require personnel to encounter high heat load, e.g., during intense physical exertion, particularly in the heat. These conditions reduce operational effectiveness and expose personnel to a risk of incapacitation and death from exertional heat illness (EHI). The aim of this study is to examine traditional and novel risk factors that may increase thermal strain and EHI likelihood in military recruits undergoing strenuous physical exercise.

Conditions

• Exertional Heat Illness

Interventions

Type	Name	Description
OTHER	Core temperature monitoring	Core temperature will be monitored on the day of exercise
BEHAVIORAL	Questionnaires	Questionnaires will be completed at baseline and on the day of exercise
OTHER	Heart rate monitoring	Heart rate will be monitored on the day of exercise
OTHER	Urine collection	Urine samples will be collected at baseline and on the day of exercise
OTHER	Sleep monitoring	Sleep will be monitored at baseline and on the day of exercise
OTHER	Blood collection	Blood samples will be completed at baseline
OTHER	Saliva collection	Saliva samples will be collected at baseline and on the day of exercise
OTHER	Throat swab collection	Throat swab samples will be collected at baseline and on the day of exercise
OTHER	Stool collection	Stool samples will be collected at baseline and on the day of exercise

Timeline

• Start date: 2021-06-11
• Primary completion: 2024-07-22
• Completion: 2025-07-01
• First posted: 2021-07-28
• Last updated: 2025-03-19

Locations

1 site across 1 country: United Kingdom