NCT04978714

USI and/or DO in Women With Cystocele Before and After Cystocele Repair

Prevalence of Urodynamic Stress Incontinence and/or Detrusor Overactivity in Women With Cystocele and the Changes of Continence Function After Cystocele Repair

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 483 (actual)
• Sponsor: National Taiwan University Hospital · Academic / Other
• Sex: Female
• Age: 20 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

The changes of lower urinary tract function after cystocele repair are important for perioperative consultation and management. Thus, the aim of this retrospective study was to evaluate the prevalence of urodynamic stress incontinence and/or detrusor overactivity in women with ≥ stage II cystocele and the changes of incontinence function after cystocele repair.

Detailed description

Between November 2010 and October 2020, all women with ≥ stage II cystocele who visited the urogynecological department of a medical center for cystocele repair were reviewed. Those women who had complete data of preoperative and postoperative 3-month follow-up urodynamic data were excluded from this study. Urodynamic stress incontinence was diagnosed by the finding of involuntary leakage during filling cystometry or stress urethral pressure profile, associated with increased intra-abdominal pressure, in the absence of a detrusor contraction. Detrusor overactivity was defined as the occurrence of involuntary detrusor contractions during filling cytometry. STATA software was used for statistical analysis. Chi2 test, univariate and multivariable logistic regression tests were used for statistical analysis as appropriate. A p \< 0.05 was considered as statistically significant.

Conditions

• Urodynamic Stress Incontinence
• Detrusor Overactivity

Interventions

Type	Name	Description
PROCEDURE	Cystocele repair	Fascial repair for endopelvic fascia and anterior colporrhaphy

Timeline

• Start date: 2010-11-01
• Primary completion: 2020-10-31
• Completion: 2020-10-31
• First posted: 2021-07-27
• Last updated: 2021-07-27

Locations

1 site across 1 country: Taiwan