NCT04975763

Dietary Oils to Sustain Energy Study

Dietary Oils to Sustain Energy (DOSE) Study: Understanding How Consumption of Dietary Oils in Foods Influences Blood Fatty Acids and Body Weight

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 16 (estimated)
• Sponsor: Ohio State University · Academic / Other
• Sex: All
• Age: 25 Years – 80 Years
• Healthy volunteers: Accepted

Summary

The research study is an intervention and feasibility crossover design pilot study designed to assess if consuming 3 study foods made with either soybean oil or palm oil per day for 4 weeks can alter whole blood, plasma and erythrocyte fatty acids and body weight in overweight/obese adults. Additionally, the study will assess the adherence to consuming 3 study foods per day for 4 weeks and to assess if participant remain unaware of (or masked to) which study food group (soybean oil vs palm oil) they are consuming.

Detailed description

The objectives of the study include * To determine changes in whole blood, plasma and erythrocyte linoleic acid after 4 weeks of consuming 3 foods products made soybean oil and determine changes in plasma and erythrocyte oleic acid and palmitic acid after 4 weeks of consuming 3 food products per day made with palm oil in overweight/obese adults * To determine changes in body weight in overweight/obese adults during four weeks of consuming 3 food products per day made with soybean oil and during four weeks of consuming 3 food products per day made with palm oil * To determine if there is evidence of unmasking of the two food product groups (soybean oil or palm oil) during the study in participants and in study coordinators * To determine adherence of consuming 3 food products per day made with either soybean or palm oil for 4 weeks in overweight/obese adults

Conditions

• Overweight and Obesity

Interventions

Type	Name	Description
OTHER	Soybean Oil Foods	Three food product containing 10g of soybean oil each will be consumed each day for a today of 30g of soybean oil consumed each day
OTHER	Palm Oil Foods	Three food product containing 10g of palm oil each will be consumed each day for a today of 30g of palm oil consumed each day

Timeline

• Start date: 2021-07-19
• Primary completion: 2025-07-30
• Completion: 2025-12-30
• First posted: 2021-07-23
• Last updated: 2025-08-11

Locations

1 site across 1 country: United States