NCT04975373

Intrauterine Hyaluronic Acid Gel for Prevention of Intrauterine Adhesions

Reduction of Intrauterine Adhesions by Intrauterine Hyaluronic Acid Gel After Hysteroscopic Removal of Retained Products of Conception: Multicenter Prospective Randomized Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 160 (estimated)
• Sponsor: Barzilai Medical Center · Academic / Other
• Sex: Female
• Age: 18 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

Women undergoing operative hysteroscopy for removal of retained placenta after delivery will be randomized into two groups. 1. study group - immediately after operative hysteroscopy 5 ml hyaluronic acid gel will be injected into uterine cavity 2. control group - no injection 4-8 weeks after operative hysteroscopy, participants will undergo diagnostic hysteroscopy with no anesthesia , as a part of routine evaluation after removal of retained placenta in Israel. during diagnostic hysteroscopy the uterine cavity will be evaluated and the presence of adhesions and severity of adhesions will be recorded.

Conditions

• Prevenetion of Intrauterine Adhesions by Hyaluronic Acid Gel

Interventions

Type	Name	Description
DRUG	Intrauterine injection of hyaluronic acid	operative hysteroscopy - as a part of treatment in cases with retained placenta after delivery diagnostic hysteroscopy - as a routine evaluation after removal of placenta

Timeline

• Start date: 2021-06-25
• Primary completion: 2022-07-25
• Completion: 2022-07-25
• First posted: 2021-07-23
• Last updated: 2021-07-23

Locations

1 site across 1 country: Israel