NCT04974229

Prognostic Factor Research of Sensory Profiles in Development of Central Sensitization

Sensory Profiles as Predictors of Central Sensitization in Low Back Pain: A Prospective Cohort Study.

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 102 (actual)
• Sponsor: Vrije Universiteit Brussel · Academic / Other
• Sex: All
• Age: 18 Years – 64 Years
• Healthy volunteers: Not accepted

Summary

A longitudinal observational cohort study to investigate the value of prognostic factors, here sensory profiles , and others, in the development of central sensitization in the low back pain population. A type 2 prognostic factor research following the PROGRESS framework. Sensory profiles are identified a prognostic factors which can predict the development of central sensitization in the low back pain population.

Detailed description

After performing an univariable linear regression analyses the regression model predicts the dependent variable, central sensitization, significantly, and the models are significant prediction factors of the development of central sensitization. In unadjusted analyses, all four sensory profiles were significantly associated with the development of central sensitization (P\<0.001). After adjusting for pain, disability, age, and duration of low back pain, baseline sensory profiles remained significant predictors of central sensitization. On the other hand, all other predictor variables did not contribute to the prediction of central sensitization.

Conditions

• Sensory Profiles
• Central Sensitisation
• Low Back Pain
• Nociplastic Pain

Interventions

Type	Name	Description
OTHER	In line with the Dutch guideline for non-specific low back pain, Standard usual care for non-specific low back pain was applied.	In line with the Dutch guideline for non-specific low back pain, Standard usual care or non-specific low back pain was applied.

Timeline

• Start date: 2016-01-01
• Primary completion: 2017-03-01
• Completion: 2017-03-01
• First posted: 2021-07-23
• Last updated: 2021-07-23

Locations

1 site across 1 country: Belgium