Clinical Trials Directory

Trials / Unknown

UnknownNCT04966975

Effect and Prognosis of Immunohistochemical Biomarkers Changes in Patients With Bladder Cancer After Neoadjuvant Chemotherapy

Status
Unknown
Phase
Study type
Observational
Enrollment
60 (estimated)
Sponsor
Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University · Academic / Other
Sex
All
Age
18 Years – 80 Years
Healthy volunteers
Not accepted

Summary

Clinical trial to investigate the relationship between the expression of immunohistochemical biomarkers GATA-3, CK20, P53 and Ki67 in bladder cancer and pathological complete response after neoadjuvant chemotherapy.

Detailed description

This is a retrospective study included bladder cancer patients treated with neoadjuvant chemotherapy. We analyzed the changes in the expression of GATA-3, CK20, P53 and Ki67 before and after NAC. Evaluating the sensitivity factor for predicting pathological complete response.

Conditions

Interventions

TypeNameDescription
OTHERneoadjuvant chemotherapyThe patients receive neoadjuvant chemotherapy for 2-4 cycles before surgery.

Timeline

Start date
2021-09-01
Primary completion
2022-08-31
Completion
2022-08-31
First posted
2021-07-19
Last updated
2021-07-19

Source: ClinicalTrials.gov record NCT04966975. Inclusion in this directory is not an endorsement.