NCT04966780

Refeeding Like Syndrome in Acute Disease

Dose-response Relation Between the Development of a Refeeding-like Syndrome and Sodium Balance in Patients Undergoing Acute Abdominal Surgery

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 48 (actual)
• Sponsor: Jens Rikardt Andersen · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The refeeding syndrome has been reported without any evidence of prolopnged semistarvation, thus being different from the traditional disease. The investigators wanted to investigate, if sodium infusions could be part of the explanation.

Detailed description

Background: Refeeding syndrome is conventionally connected to start of feeding after prolonged periods of semi-starvation and adaption. However, it is also described in acutely ill patients and in ICU patients without a history of adaption, but sometimes only defined as a drop in p-phosphate without clinical manifestations. The investigators hypothesize, that a positive sodium balance could induce the refeeding-like syndrome (RLS). Method: Consecutive patients for acute, abdominal surgery were included and observed until discharge or up to seven days postoperatively with daily sodium and phosphate balance measurements.

Conditions

• Refeeding Syndrome
• Acute Abdomen

Interventions

Type	Name	Description
PROCEDURE	acute abdominal surgery	Acute surgery for acute abdominal disease

Timeline

• Start date: 2018-04-01
• Primary completion: 2021-06-01
• Completion: 2021-06-01
• First posted: 2021-07-19
• Last updated: 2021-07-26

Locations

1 site across 1 country: Denmark