Clinical Trials Directory

Trials / Completed

CompletedNCT04965870

A Study of Trifluridine/ Tipiracil in Chemorefractory mCRC in Greece

A Retrospective Observational Study of Trifluridine/ Tipiracil (TAS-102) in Chemorefractory Metastatic Colorectal Cancer (mCRC) in Greece. Real World Data on Clinical Benefit.

Status
Completed
Phase
Study type
Observational
Enrollment
200 (actual)
Sponsor
Hellenic Study Group of Psychoneuroimmunology in Cancer · Network
Sex
All
Age
18 Years – 90 Years
Healthy volunteers
Not accepted

Summary

Collection of real world data on the clinical efficacy of trifluridine/ tipiracil (FTD/TPI) in the Greek population.

Detailed description

The aim of this analysis is to record clinical practice and to collect real world data on the clinical efficacy of trifluridine/ tipiracil (FTD/TPI) in the Greek population. Main objectives include to assess physician's choice of treatment in chemoresistant metastatic colorectal cancer with FTD/TPI in third line and beyond In addition, the clinicopathologic features related to metastatic colorectal cancer (focus on molecular profile), duration of treatment, dose modification and toxicity will be analyzed.

Conditions

Interventions

TypeNameDescription
DRUGTrifluridine/TipiracilTrifluridine/ Tipiracil is an oral combination of an antineoplastic thymidine-based nucleoside analogue, trifluridine, and the thymidine phosphorylase (TPase) inhibitor, tipiracil hydrochloride.

Timeline

Start date
2021-06-30
Primary completion
2021-10-31
Completion
2021-12-20
First posted
2021-07-16
Last updated
2022-03-07

Locations

8 sites across 1 country: Greece

Source: ClinicalTrials.gov record NCT04965870. Inclusion in this directory is not an endorsement.