Clinical Trials Directory

Trials / Active Not Recruiting

Active Not RecruitingNCT04965792

Post-treatment Surveillance in HPV+ Oropharyngeal SCC

Circulating HPV DNA for Post-treatment Surveillance in HPV-positive Oropharyngeal Squamous Cell Carcinoma

Status
Active Not Recruiting
Phase
Study type
Observational
Enrollment
150 (estimated)
Sponsor
Dana-Farber Cancer Institute · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

In this research study the investigators are examining a blood test to detect HPV DNA in the blood that can possibly detect cancer recurrence earlier than with standard surveillance measures.

Detailed description

This research study involves blood tests to detect HPV DNA at regular time points after treatment for HPV-positive oropharyngeal squamous cell carcinoma (HPV-OPC). Participants may undergo scans based on the results of the blood tests. Study participants will also be asked to complete quality of life questionnaires periodically. Participation in this study may last for up to 3 years. It is expected that about 150 people will take part in this research study.

Conditions

Interventions

TypeNameDescription
OTHERScreeningBlood test

Timeline

Start date
2020-11-19
Primary completion
2026-11-01
Completion
2027-11-01
First posted
2021-07-16
Last updated
2025-06-17

Locations

1 site across 1 country: United States

Source: ClinicalTrials.gov record NCT04965792. Inclusion in this directory is not an endorsement.