NCT04964739

Gender/Sex & CUD Remission

Gender and Sex Hormone Influences on Cannabis Use Disorder Remission

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 224 (actual)
• Sponsor: Medical University of South Carolina · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Adults (ages 18+) who would like to reduce their cannabis use (N=224) will be enrolled in an 8-week treatment program. All participants will receive counseling (1 goals session with a therapist followed by 7 weekly computerized cognitive-behavioral therapy sessions). Detailed cannabis assessments (biological and self-report) will be conducted throughout treatment and at 1-, 2-, and 3-months post-treatment completion. Daily electronic diaries will be administered via text message to record detailed logs of cannabis use quantity and frequency. Salivary samples will be collected (and video observed) daily throughout treatment to analyze for progesterone.

Conditions

• Cannabis Use Disorder, Mild
• Cannabis Use Disorder, Moderate
• Cannabis Use Disorder, Severe

Interventions

Type	Name	Description
BEHAVIORAL	Cognitive Behavioral Therapy (CBT4CBT)	Participants will receive one therapist-led motivational interviewing/goal setting session followed by 7 sessions of computerized CBT4CBT.

Timeline

• Start date: 2021-11-15
• Primary completion: 2025-10-27
• Completion: 2025-10-27
• First posted: 2021-07-16
• Last updated: 2025-11-10

Locations

1 site across 1 country: United States