NCT04963309

Extubation in the Operating Room After Living Donor Liver Transplantation

Extubation in the Operating Room After Living Donor Liver Transplantation in Adult Patients: a Retrospective Observational Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 277 (actual)
• Sponsor: Pusan National University Yangsan Hospital · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Duration of mechanical ventilation, length of intensive care unit stay, length of postoperative hospital stay, and the incidence rates of complications between the group with endotracheal tube extubation in the operating room (OR-EX) and those without (NOR-EX) in patients who underwent living-donor liver transplantation for end-stage liver failure are going to be compared. Through these results, it is investigated whether endotracheal tube extubation in the operating room is useful in reducing the length of stay in the intensive care unit and the hospital stay after surgery in patients who have undergone living-donor liver transplantation.

Detailed description

Long-term mechanical ventilation after liver transplantation may increase the risk of complications such as pneumonia, sepsis, and multi-organ failure. Recent advances in surgical techniques and the introduction of short-acting anesthetics have accelerated the recovery of liver transplant recipients, and early extubation after liver transplantation is being proposed as a standard method. The results of a study on early extubation in patients undergoing liver transplantation suggested a reduction in the length of stay in the neutralizer room and predictors of early extubation. However, these studies are limited to males, and there is no study in which the definition of early extubation includes extubation in the operating room or extubation in the operating room within 1-3 hours of arrival in the intensive care unit.

Conditions

• Extubation in the OR After LDLT

Interventions

Type	Name	Description
OTHER	endotracheal tube extubation in the operating room	endotracheal tube extubation in the operating room

Timeline

• Start date: 2021-03-01
• Primary completion: 2021-06-29
• Completion: 2021-06-29
• First posted: 2021-07-15
• Last updated: 2021-07-15

Locations

1 site across 1 country: South Korea