NCT04962074

Sperm Selection and Embryo Development: Comparison of the Density Gradient Centrifugation and Microfluidic Chip Sperm Preparation Methods Sperm Selection and Embryo Development: Comparison of the Density Gradient Centrifugation and Microfluidic Chip Sperm Preparation Methods

Sperm Selection and Embryo Development: Comparison of the Density Gradient Centrifugation and Microfluidic Chip Sperm Preparation Methods

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 22 (actual)
• Sponsor: Maltepe University · Academic / Other
• Sex: Male
• Age: —
• Healthy volunteers: Not accepted

Summary

Purpose: To compare the effects of the density gradient centrifugation and microfluidic chip sperm preparation methods on embryo development in a study population with astheno-teratozoospermia. Materials and Methods: In this prospective study, the semen samples of the patients with astheno-teratozoospermia were divided into two groups for preparation with either the microfluidic or density gradient methods. Selected spermatozoa were used to fertilize the mature sibling oocytes. Semen parameters and embryo development on days 3 and 5 were assessed.

Conditions

• Reduced Sperm Motility
• IVF
• ICSI
• Astheno Teratozoospermia

Interventions

Type	Name	Description
DEVICE	Microfluidic sperm sorting chip	Fertile Ultimate® (Koek Biotechnology, Turkey) microfluidic sperm sorting chips
DEVICE	Density gradient	Density gradient centrifugation

Timeline

• Start date: 2020-01-05
• Primary completion: 2020-09-20
• Completion: 2020-09-20
• First posted: 2021-07-14
• Last updated: 2021-07-14

Locations

1 site across 1 country: Turkey (Türkiye)