NCT04961970

HAIC With FOLFOX Versus Systemic Chemotherapy With GP for Unresectable ICC

Hepatic Arterial Infusion Chemotherapy of Oxaliplatin, 5-Fluorouracil and Leucovorin Versus Systemic Chemotherapy of Gemcitabine and Cisplatin for Unresectable Intrahepatic Cholangiocarcinoma

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 188 (estimated)
• Sponsor: Shi Ming · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate the efficacy and safety of hepatic arterial infusion chemotherapy (HAIC) of oxaliplatin, 5-fluorouracil and leucovorin compared systemic chemotherapy of gemcitabine and cisplatin in patients with unresectable intrahepatic cholangiocarcinoma.

Conditions

• Intrahepatic Cholangiocarcinoma

Interventions

Type	Name	Description
DRUG	oxaliplatin , fluorouracil, and leucovorin	administration of oxaliplatin , fluorouracil, and leucovorin via the tumor feeding arteries
DRUG	gemcitabine and cisplatin	administration of gemcitabine and cisplatin via vein

Timeline

• Start date: 2021-07-09
• Primary completion: 2025-07-09
• Completion: 2025-07-09
• First posted: 2021-07-14
• Last updated: 2021-07-14

Locations

1 site across 1 country: China