Trials / Completed
CompletedNCT04960878
The Effect of Synbiotics on the Upper Respiratory Tract Infection
The Effect of Synbiotics on the Upper Respiratory Tract Infection in Healthy Subjects: A Randomized Double-Blind Trial
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 58 (actual)
- Sponsor
- Huazhong University of Science and Technology · Academic / Other
- Sex
- All
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Accepted
Summary
Gut microbiome manipulation to alter the gut-lung axis may potentially protect humans against respiratory infections. However, clinical trials of synbiotics, one of the microbiota-targeted intervention, in this regard is few. Therefore, this study aims to examine the effect of synbiotics on the incidence and severity of upper respiratory tract infection, gut microbiota composition and function, as well as biomarkers of immune function.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Synbiotic | Synbiotics sachet mainly contained Lactobacillus rhamnosus HN001, Bifidobacterium lactis HN019, and fructooligosaccharides. |
| DIETARY_SUPPLEMENT | Placebo | Maltodextrin |
Timeline
- Start date
- 2020-10-05
- Primary completion
- 2020-12-20
- Completion
- 2021-01-05
- First posted
- 2021-07-14
- Last updated
- 2021-07-14
Locations
1 site across 1 country: China
Source: ClinicalTrials.gov record NCT04960878. Inclusion in this directory is not an endorsement.