NCT04960033

Evaluating Fracture Risk Assessment Tools (FRAX) From Different Regions in Central South Chinese Postmenopausal Women

Central South University

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 264 (actual)
• Sponsor: Central South University · Academic / Other
• Sex: Female
• Age: 50 Years
• Healthy volunteers: Accepted

Summary

We evaluated fracture risk assessment tools (FRAXs) from different regions in Chinese postmenopausal women.

Detailed description

This cross-sectional study recruited 264 postmenopausal women aged ≥50 years in September 2017. Basic information, general condition, history of illness, family history, and clinical risk factors were evaluated via a questionnaire. All subjects underwent a bone mineral density examination of the femur and lumbar spine and thoracolumbar spinal X-ray. The 10-year major osteoporotic fracture (MOF) and hip fracture (HF) risks were calculated using FRAXs from mainland China, Hong Kong, Taiwan, and Asia-America. All data were analyzed using SPSS 17.0. Sensitivity, specificity, and likelihood ratio were used to compare the effectiveness of each FRAX.

Conditions

• Osteoporosis Fracture

Interventions

Type	Name	Description
BEHAVIORAL	FRAX	The 10-year MOF probability and the 10-year HF probability were calculated using the FRAXs of different regions (mainland China, Hong Kong, Taiwan, and Asia-America). Subjects were deemed as high-risk for osteoporotic fracture if the 10-year probability of MOF was ≥20% or the 10-year probability of HF was ≥3%.

Timeline

• Start date: 2017-09-01
• Primary completion: 2017-09-30
• Completion: 2017-09-30
• First posted: 2021-07-13
• Last updated: 2021-07-13

Locations

1 site across 1 country: China