NCT04956601

Adjuvant Radiotherapy in Patients With Early Endometrial Cancer

A Multicenter, Randomized, Controlled Trial of Adjuvant Radiotherapy in Patients With Early Endometrial Cancer Based on Moderate Risk Molecules Classification

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 480 (estimated)
• Sponsor: Peking University Third Hospital · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

To compare the effect of vaginal brachytherapy as adjuvant treatment after operation when compared to pelvic external beam radiotherapy in patients with early endometrial cancer based on moderate risk molecules classification.

Detailed description

After being informed the study and potential risk，all patients giving written informed consent will be undergo a 1-week screening period determine eligibility for study entry. At week 0, patients who meet the eligibility will be randomized in a 1:1 ratio to vaginal brachytherapy or pelvic external beam radiotherapy. After treatment, patients were followed up regularly.

Conditions

• Endometrial Cancer
• Pathology
• Radiotherapy

Interventions

Type	Name	Description
RADIATION	vaginal brachytherapy/pelvic external beam radiotherapy	high-dose-rate vaginal brachytherapy; pelvic external beam radiotherapy

Timeline

• Start date: 2021-07-01
• Primary completion: 2024-08-01
• Completion: 2029-08-01
• First posted: 2021-07-09
• Last updated: 2021-07-09

Locations

1 site across 1 country: China