Trials / Unknown

UnknownNCT04952974

B-cell Chronic Lymphoid Malignancies Markers

Study of Cell Markers of Marginal Zone Lymphoma and Other B-cell Chronic Lymphoid Malignancies

Status: Unknown
Phase: —
Study type: Observational
Enrollment: 420 (estimated)

Sponsor: University Hospital, Strasbourg, France · Academic / Other
Sex: All
Age: 18 Years
Healthy volunteers: Not accepted

Summary

Lymphoid chronic B-cell malignancies are frequent pathologies that affect adults, with a very variable prognosis and treatment (some of them can remain untreated). The diagnosis of these malignancies relies on the study of the morphology of tumoral cells and the expression by these cells of several markers, mainly via a technical approach called flow cytometry. Because the markers currently used remain imperfect, additional ones are needed for an accurate diagnosis that affect both prognosis and treatment. In addition, because numerous markers are used at the diagnosis, there is a need of tools that synthetize the multi-dimensional structure of the data obtained. The primary purpose of this study is to detect new markers that can be of help for the diagnosis of Marginal Zone Lymphoma and other B-cell chronic lymphoid malignancies. The secondary purpose of this study is to obtain a statistical algorithm that allow a good prediction of the different sub-types of chronic B-cell malignancies mainly using the results of flow cytometry.

Conditions

Timeline

Start date: 2021-06-14
Primary completion: 2023-01-30
Completion: 2023-03-30
First posted: 2021-07-07
Last updated: 2021-07-07

Locations

1 site across 1 country: France

Source: ClinicalTrials.gov record NCT04952974. Inclusion in this directory is not an endorsement.