NCT04949451

Time Restricted Feeding, Muscle, and Metabolism

Time Restricted Feeding Intervention for Muscle and Metabolic Health (TRIMM)

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 90 (estimated)
• Sponsor: University of Arkansas, Fayetteville · Academic / Other
• Sex: All
• Age: 25 Years – 50 Years
• Healthy volunteers: Accepted

Summary

Effective nutrition strategies for combatting and/or preventing obesity still need to be identified. This has been the case despite the numerous and different approaches that have been taken. Potential targets for combatting/preventing obesity have been identified, but long-term solutions have not emerged. This study uses time restricted feeding to study the role of dietary protein in obesity prevention and/or treatment. The objectives are to determine the role of skeletal muscle mass as a driver of energy-sensing mechanisms and peripheral signals that regulate appetite and energy intake in overweight and obese adults and to determine the effects of protein timing on muscle mass to regulate appetite and energy intake in overweight and obese adults.

Conditions

• Overweight
• Obesity

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Whey protein supplement	Participants consume whey protein at the beginning of the eating period.
DIETARY_SUPPLEMENT	Ketogenic aid	Participants consume ketogenic aid upon waking.
OTHER	Control group - time restricted feeding only	Time restricted feeding.

Timeline

• Start date: 2021-06-13
• Primary completion: 2025-04-30
• Completion: 2025-12-30
• First posted: 2021-07-02
• Last updated: 2025-08-26

Locations

1 site across 1 country: United States