Trials / Completed
CompletedNCT04945135
Controlled Donors After Circulatory Death and Brain Death: a Multicenter Study of Transfusion, One-year Graft Survival and Mortality. Cohort Study,
Controlled Donors After Circulatory Death and Brain Death: a Multicenter Study of
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 591 (actual)
- Sponsor
- Hospital Clinic of Barcelona · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
RBC requirement ein DBD and DCD liver transplants
Detailed description
Background: Controlled donation after cardiac circulatory death (cDCD) is accepted to expand the donor pool for liver transplantation (LT). However, transfusion requirements and perioperative outcomes should be elucidated. The aims of this multicentre study are to assess the red blood cell (RBC) transfusions, one-year graft and patient survival after LT with cDCD compared to donors after brain dead (DBD). Methods: 591 LT patients conducted in ten centers during 2019 were reviewed. Thromboelastometry was used to manage coagulation and blood product transfusion in all centres. Normothermic regional perfusion was the standard technique for organ recovery.
Conditions
Timeline
- Start date
- 2019-06-01
- Primary completion
- 2020-01-01
- Completion
- 2021-06-25
- First posted
- 2021-06-30
- Last updated
- 2021-06-30
Locations
2 sites across 1 country: Spain
Source: ClinicalTrials.gov record NCT04945135. Inclusion in this directory is not an endorsement.