NCT04941950

A Digital Intervention to Prevent the Initiation of Opioid Misuse in Adolescents in School-based Health Centers

A Digital Intervention to Prevent the Initiation of Opioid Misuse in Adolescents in School-based Health Centers (Randomized Controlled Trial)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 533 (actual)
• Sponsor: Trustees of Dartmouth College · Academic / Other
• Sex: All
• Age: 16 Years – 19 Years
• Healthy volunteers: Accepted

Summary

The primary hypothesis of this study is that at 3 months, there will be a higher proportion of intervention participants vs. control participants who report greater risk of harm from misuse of prescription opioids AND heroin.

Detailed description

This study's specific aims are to: Conduct a randomized controlled trial with 532 high-risk adolescents in 10 School Based Health Centers (SBHCs), to compare PlaySmart to attention/time control games, with assessments post- gameplay (6 weeks), and at 3, 6, and 12 months following enrollment to determine if PlaySmart: 1) increases proportion of participants who report a perception of great risk of harm from misuse of opioids at 3 months; and 2) decreases intentions to misuse opioids; 3) increases self-efficacy for refusing opioids; 4) prevents initiation of opioid misuse, at all time-points.

Conditions

• Opioid Misuse

Interventions

Type	Name	Description
BEHAVIORAL	PlaySmart	PlaySmart is designed to provide players with behavioral skills and knowledge through repetitive and engaging videogame play to target adolescent perception of risk of harm from initiating opioid misuse.
OTHER	Video Game Control	Participants in the control group will play another video game with no intended effect similar to PlaySmart.

Timeline

• Start date: 2021-10-19
• Primary completion: 2025-03-01
• Completion: 2025-03-01
• First posted: 2021-06-28
• Last updated: 2025-04-03

Locations

15 sites across 1 country: United States