Clinical Trials Directory

Trials / Completed

CompletedNCT04941027

Evaluating Genetic Modifiers of Cutaneous Neurofibromas in Adults With Neurofibromatosis Type 1

Status
Completed
Phase
Study type
Observational
Enrollment
1,046 (actual)
Sponsor
Stanford University · Academic / Other
Sex
All
Age
40 Years
Healthy volunteers
Not accepted

Summary

The main goal of this protocol is to develop a well-phenotyped genetic biobank to identify genetic variants associated with the heterogeneous clinical presentations of Neurofibromatosis Type 1 (NF1). This will allow for improve understanding of NF1 pathogenesis and more personalized disease management. The investigators will conduct a GWAS analysis to identify common genetic risk variants associated with the development of cutaneous neurofibromas.

Conditions

Timeline

Start date
2021-05-07
Primary completion
2025-09-30
Completion
2025-11-24
First posted
2021-06-28
Last updated
2025-12-02

Locations

2 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT04941027. Inclusion in this directory is not an endorsement.