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Trials / Completed

CompletedNCT04940559

Study of Different Forms of Danicopan (Tablet, Softgel Capsule, Liquid-filled Capsule) in Healthy Participants

A Phase 1 Study To Determine The Relative Bioavailability Of ACH-0144471 After Administration Of A Tablet Or Softgel Capsule Versus A Liquid Filled Capsule In Healthy Volunteers

Status
Completed
Phase
Phase 1
Study type
Interventional
Enrollment
26 (actual)
Sponsor
Alexion Pharmaceuticals, Inc. · Industry
Sex
All
Age
18 Years – 55 Years
Healthy volunteers
Accepted

Summary

This was a randomized, crossover, open-label study to assess the relative bioavailability, pharmacokinetics (PK), and safety of three different formulations of danicopan (tablet, softgel capsule, liquid-filled capsule \[LFC\]) in healthy participants.

Conditions

Interventions

TypeNameDescription
DRUGDanicopan - TabletOral tablet.
DRUGDanicopan - SoftgelOral softgel capsule.
DRUGDanicopan - LFCOral LFC.

Timeline

Start date
2016-08-02
Primary completion
2016-10-05
Completion
2016-10-05
First posted
2021-06-25
Last updated
2021-06-25

Locations

1 site across 1 country: New Zealand

Source: ClinicalTrials.gov record NCT04940559. Inclusion in this directory is not an endorsement.

Study of Different Forms of Danicopan (Tablet, Softgel Capsule, Liquid-filled Capsule) in Healthy Participants (NCT04940559) · Clinical Trials Directory