Trials / Completed
CompletedNCT04938284
Combining PAS to Non-invasive VNS
The Synergistic Effect of Paired Associative Stimulation and Vagus Nerve Stimulation on Motor-evoked Potential Potentiation in Healthy Subjects
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 10 (actual)
- Sponsor
- Helsinki University Central Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Accepted
Summary
Vagus nerve stimulation (VNS) and paired associative stimulation (PAS) have been shown to have efficacy in improving the results of motor rehabilitation after stroke and spinal cord injury, respectively. Here we will investigate in healthy subjects the synergistic effect of these stimulation modalities on motor-evoked potential (MEP) potentiation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DEVICE | PAS | Paired associative stimulation is a combination of non-invasive transcranial magnetic stimulation (TMS) and non-invasive peripheral nerve stimulation (PNS) |
| DEVICE | VNS | Non-invasive vagus nerve stimulation delivered through cymba concha \& cymba cavum of the ear. |
Timeline
- Start date
- 2021-07-01
- Primary completion
- 2021-12-30
- Completion
- 2021-12-30
- First posted
- 2021-06-24
- Last updated
- 2025-05-13
Locations
1 site across 1 country: Finland
Source: ClinicalTrials.gov record NCT04938284. Inclusion in this directory is not an endorsement.